The typical time of life when sex hormone issues do appear is 35 – 59, when perimenopause and menopause often occur; the average age for actual menopause is said to be 52. Perimenopause – the signs and effects of the menopause transition – can begin as early as age 35, although most women become aware of the transition in their mid to late 40s. During perimenopause, which can last Continue Reading about What Are Perimenopause and Menopause?