Do patients need progesterone when they use the pellets?Any time estradiol is prescribed and a woman still has her uterus, progesterone must be prescribed. Progesterone is most effective as an oral capsule, and tends not to hold together well in pellet form, so it is generally not used in pellet form.Is hormone pellet therapy only for women in menopause?Definitely not! Women at any age may Continue Reading about Do You Have Questions About Hormone Pellet Therapy?